{"id":71925,"date":"2021-08-27T21:00:12","date_gmt":"2021-08-27T21:00:12","guid":{"rendered":"https:\/\/papivax.com\/?page_id=71925"},"modified":"2021-10-29T05:54:59","modified_gmt":"2021-10-29T05:54:59","slug":"hpv","status":"publish","type":"page","link":"https:\/\/papivax.com\/zh\/hpv\/","title":{"rendered":"\u4f73\u63da\u7684\u670d\u52d9"},"content":{"rendered":"

[vc_row type=”container”][vc_column][vc_column_text]<\/p>\n

\u4eba\u4e73\u982d\u7624\u75c5\u6bd2 (HPV) \u662f\u6700\u5e38\u898b\u7684\u6027\u50b3\u64ad\u611f\u67d3\u3002 \u67d0\u4e9b\u9ad8\u5371\u578b HPV \u662f\u5e7e\u4e4e\u6240\u6709\uff08\u7d04 99%\uff09\u5973\u6027\u5bae\u9838\u764c\u75c5\u4f8b\u548c\u5168\u7403\u6240\u6709\u764c\u75c7\u7684 4.5% \u7684\u5fc5\u8981\u539f\u56e0\u3002<\/span><\/h4>\n

HPV \u5c0d\u5bae\u9838\u764c\u7684\u300c\u6b78\u56e0\u5206\u6578\u300d\uff08attributable fraction,\u7c21\u7a31 AF\uff09\u662f\u5e7e\u4e4e 100%\uff08\u5373 HPV \u662f\u5bae\u9838\u764c\u7684\u552f\u4e00\u75c5\u56e0\uff09\uff0c\u800c\u4e14 HPV \u9084\u5c0e\u81f4 15-88% \u7684\u5916\u9670\u764c\u3001\u9670\u9053\u764c\u3001\u9670\u8396\u764c\u548c\u809b\u9580\u764c\uff1b\u81f3\u65bc\u53e3\u54bd\/\u982d\u9838\u90e8\u764c\u65b9\u9762\uff0cHPV \u5728\u67d0\u4e9b\u570b\u5bb6\u7684 AF \u7d04 30% ref<\/a>\uff0c\u800c\u5728\u7f8e\u570b\u7b49\u5176\u4ed6\u897f\u65b9\u570b\u5bb6\u5247\u53ef\u9ad8\u9054 70%\u3002<\/p>\n

HPV \u76f8\u95dc\u764c\u75c7\u7684\u65e2\u5b9a\u6cbb\u7642\u65b9\u6cd5\u5305\u62ec\u624b\u8853\u3001\u653e\u7642\u548c\u5316\u7642\u3002\u5c0d\u65bc\u7121\u6cd5\u63a5\u53d7\u624b\u8853\u6cbb\u7642\u7684\u764c\u75c7\u60a3\u8005\uff08\u56e0\u764c\u75c7\u8a3a\u65b7\u6642\u5df2\u662f\u5c40\u90e8\u665a\u671f\uff0c\u6216\u5df2\u7522\u751f\u9060\u7aef\u8f49\u79fb\uff0c\u6216\u5728\u63a5\u53d7\u521d\u59cb\u6cbb\u7642\u5f8c\u764c\u75c7\u5fa9\u767c\uff09\uff0c\u90fd\u5efa\u8b70\u55ae\u7368\u6216\u7d50\u5408\u653e\u7642\u8207\u5316\u7642\uff08\u5316\u653e\u7642\uff09\uff0c\u6709\u6642\u518d\u52a0\u4e0a\u8a66\u9a57\u6027\u65b0\u85e5\u9032\u884c\u8f14\u52a9\u6cbb\u7642\uff08adjuvant therapy\uff09\u3002\u8fd1\u5e74\u4f86 PD-1\/PD-L1 \u514d\u75ab\u6aa2\u67e5\u9ede\u6291\u5236\u5291\u7d93\u904e\u81e8\u5e8a\u8a66\u9a57\u8b49\u5be6\u5c0d\u4e9b\u8a31\u6b64\u985e\u60a3\u8005\uff08\u5c24\u5176\u662f\u6709 PD-L1 \u967d\u6027\u8868\u73fe\u7684\u816b\u7624\uff09\u6709\u986f\u8457\u7642\u6548\uff08\u5ef6\u9577\u5b58\u6d3b\u671f\u3001\u589e\u9ad8\u5b58\u6d3b\u7387\uff09\uff0c\u64da\u7814\u7a76\u5831\u5c0e\u6709 10-20% \u60a3\u8005 ref<\/a> \u80fd\u5c0d\u6b64\u514d\u75ab\u8f14\u52a9\u6cbb\u7642\u6709\u6301\u4e45\u53cd\u61c9\u3002\u4f73\u63da\u751f\u6280 \u7684\u6cbb\u7642\u6027\u75ab\u82d7 PVX7 \u985e\u4f3c\u4f46\u4e0d\u540c\u65bc\u514d\u75ab\u6aa2\u67e5\u9ede\u6291\u5236\u5291\uff0c\u6240\u4ee5\u4f5c\u70ba\u6b64\u985e\u75c5\u60a3\u53e6\u4e00\u7a2e\u65b0\u7684\u8f14\u52a9\u514d\u75ab\u7642\u6cd5\u7684\u6f5b\u529b\u975e\u5e38\u96c4\u539a\u3002<\/p>\n

\"\"<\/p>\n

\u6839\u64da\u7f8e\u570b CDC \u5c0d HPV \u76f8\u95dc\u7684\u5404\u7a2e\u764c\u75c7\u548c\u5176\u6b78\u56e0\u5206\u6578\u767c\u5e03\u7684\u7d71\u8a08\u6578\u5b57\uff08\u898b\u4e0a\u8868\uff09\uff0c\u4f30\u8a08\u5168\u570b\u5728 2013 \u5230 2017 \u5e74\u9593\u5e73\u5747\u6bcf\u5e74\u6709\u7d04\u4e09\u842c\u4e94\u5343\u4e5d\u767e\uff0835,900\uff09\u540d HPV \u76f8\u95dc\u764c\u75c7\u7684\u65b0\u60a3\u8005\uff08\u5e74\u767c\u75c5\u7387,\u6216 annual incidence\uff09\uff1b\u9019\u4e9b\u75c5\u4eba\u4e2d\uff0c\u4ee5\u60a3\u53e3\u54bd\u764c\uff0814,000 \u4eba\uff09\u548c\u5bae\u9838\u764c\uff0811,000 \u4eba\uff09\u7684\u6700\u591a\uff0c\u800c\u4e14\u5973\u6027\uff0821,100 \u4eba\uff09\u591a\u65bc\u7537\u6027\uff0814,800 \u4eba\uff09\u3002\u6839\u64da\u7f8e\u570b NIH SEER\uff08\u76e3\u6e2c\u3001\u6d41\u884c\u75c5\u5b78\u548c\u6700\u7d42\u7d50\u679c\uff09\u8a08\u5283\u5831\u544a\u7684\u7d71\u8a08\u6578\u64da\uff0c2018 \u5e74\u7f8e\u570b\u5bae\u9838\u764c\u7684\u4f30\u8a08\u60a3\u75c5\u7387(prevalence)\u70ba 293,394\u3002\u9664\u6b64\u4e4b\u5916\uff0c\u540c\u6642\u7f79\u60a3\u9019\u4e9b\u764c\u75c7\u7684\u75c5\u4eba\u7e3d\u6578\uff08\u6d41\u884c\u7387,\u6216 prevalence\uff09\u662f\u5e74\u767c\u75c5\u7387\u7684\u5341\u5e7e\u3001\u4e8c\u5341\u500d\u4e4b\u591a\uff08\u898b\u4e0a\u8868\uff09\u3002\u6b50\u6d32 2012 \u5e74\u7684\u985e\u4f3c\u7d71\u8a08\u6578\u5b57\u66f4\u662f\u7f8e\u570b\u7684\u5169\u500d\u9084\u591a ref<\/a>\uff1b\u5728\u6b50\u7f8e\u4ee5\u5916\u7684\u5730\u5340\u4e2d\uff0c\u8207 HPV \u76f8\u95dc\u7684\u764c\u75c7\u75c5\u4eba\u66f4\u591a\u3002\u9019\u4e9b\u773e\u591a\u75c5\u60a3\u4e2d\u6709\u4e0d\u5c11\u4eba\u7684\u764c\u75c7\u53ef\u4ee5\u53d7\u60e0\u65bc\u63a5\u53d7\u985e\u4f3c PVX7 \u6cbb\u7642\u6027\u75ab\u82d7\u7684\u8f14\u52a9\u6cbb\u7642\u3002[\/vc_column_text][\/vc_column][\/vc_row][vc_row type=”container”][vc_column][vc_column_text]<\/p>\n

[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

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